FADS1 ELISA Kit for Human(Homo sapiens) | EIAab.comFADS1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > FADS1(Gene name) > Human

FADS1 (Gene name),

Fatty acid desaturase 1 (Protein name ), FADS1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FADS1(FADSD5);

Protein name:

Fatty acid desaturase 1;

Alternative:

Delta(5) fatty acid desaturase(D5D;Delta(5) desaturase;Delta-5 desaturase);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively.

Subcellular Location:

Endoplasmic reticulum membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

444

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

444:

PLVQSLCAKH | GIEYQSKPLL | SAFADIIHSL | KESGQLWLDA | YLHQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O60427

UniGene:

Hs.503546

SMR:

O60427

KEGG:

hsa:3992

Pfam:

PF00173

MIM:

606148

Uniprot:

O60427

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ELISA Kit for Human Fatty acid desaturase 1

Cat.:

E0671h

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96T

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ELISA Kit for Human Fatty acid desaturase 1

Cat.:

E0671m

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Packing:

96T

ELISA Kit for Human Fatty acid desaturase 1

Cat.:

E0671r

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96T

CLIA Kit for Human Fatty acid desaturase 1

Cat.:

U0671h

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Packing:

96T

CLIA Kit for Human Fatty acid desaturase 1

Cat.:

U0671m

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MSDS:

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Packing:

96T

CLIA Kit for Human Fatty acid desaturase 1

Cat.:

U0671r

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96T

Polyclonal Antibody for Human Fatty acid desaturase 1

Cat.:

P0671Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Fatty acid desaturase 1

Cat.:

P0671Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Fatty acid desaturase 1

Cat.:

P0671Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Fatty acid desaturase 1

Protein for Human Fatty acid desaturase 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning, expression, and fatty acid regulation of the human Delta-5 desaturase."
Cho H.P. , Nakamura M. , Clarke S.D.
J. Biol. Chem.274:37335-37339(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
2.

"cDNA cloning and characterization of human Delta5-desaturase involved in the biosynthesis of arachidonic acid."
Leonard A.E. , Kelder B. , Bobik E.G. , Chuang L.-T. , Parker-Barnes J.M. , Thurmond J.M. , Kroeger P.E. , Kopchick J.J. , Huang Y.-S. , Mukerji P.
Biochem. J.347:719-724(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
tissue: Liver.
3.

"cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family."
Marquardt A. , Stoehr H. , White K. , Weber B.H.
Genomics66:175-183(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
tissue: Retina.
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Cerebellum.
tissue: Neuroblastoma.
tissue: Teratocarcinoma.
5.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Melanoma.
6.

Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Kidney epithelium.
7.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT SER-272
tissue: Brain.
9.

"A novel FADS1 isoform potentiates FADS2-mediated production of eicosanoid precursor fatty acids."
Park W.J. , Kothapalli K.S. , Reardon H.T. , Lawrence P. , Qian S.B. , Brenna J.T.
J. Lipid Res.53:1502-1512(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION (ISOFORM 1);INDUCTION
10.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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